产品货号：
Z36056
中文名称：
PPP3CA抗体
英文名称：
Anti-PPP3CA Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PPP3CA Antibody |
| 指标别名 | Calcineurin A alpha;CALN;CALNA;CALNA1;CAM PRP catalytic subunit;CCN1;CNA;CNA1;PPP2B;PPP3CA |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM |
| 基因名称 | PPP3CA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Calcineurin A |
| 实际分子量 | 59KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Calcineurin A is also known as PPP3CA.It is mapped to 4q24.Semsarian et al.(1999) and Musaro et al.(1999) independently showed that IGF1stimulates skeletal muscle hypertrophy and a switch to glycolytic metabolism by activating calcineurin A and inducing the nuclear translocation of transcription factor NFATC1.Semsarian et al.(1999) found that hypertrophy was suppressed by the calcineurin inhibitors cyclosporin A or FK506,but not by inhibitors of the MAP kinase or phosphatidylinositol-3-OH kinase pathways.Musaro et al.(1999) showed that expression of a dominant-negative calcineurin mutant also repressed myocyte differentiation and hypertrophy.Musaro et al.(1999) demonstrated that either IGF1 or activated calcineurin induces expression of transcription factor GATA2,which accumulates in a subset of myocyte nuclei,where it associates with calcineurin and a specific dephosphorylated isoform of NFATC1. |
| Uniprot ID | Q08209 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Flow cytometry (FCM) 1:20 |
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